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Hyro

  • New York, NY
  • Founded 2018
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Hyro is the leading responsible AI agent platform for healthcare, enabling health systems to automate patient communications across call centers, websites, SMS, and mobile apps with HIPAA-compliant voice and chat AI agents that resolve over 85% of routine interactions.

Perfect for

Hyro is best suited for mid-to-large healthcare organizations, particularly multi-site health systems and hospitals, that need to automate high-volume patient communications across call centers and digital channels while maintaining strict HIPAA compliance.

  • Health systems with overburdened call centers experiencing long wait times, high call abandonment rates, and staff burnout from repetitive inquiries
  • Hospitals and clinics running Epic EHR that want to automate scheduling, MyChart password resets, and prescription management
  • Patient access and contact center leaders seeking to reduce operational costs while improving 24/7 patient self-service capabilities
  • Children's hospitals needing specialized pediatric access workflows including caregiver proxy scheduling and multilingual support
  • Healthcare organizations using Five9, Cisco, Genesys, NICE, or Avaya contact center platforms looking to layer AI automation without replacing existing infrastructure

Key strengths

  • Healthcare-specific AI with responsible AI framework (explainability, control, compliance) that prevents hallucinations by grounding responses exclusively in approved organizational content

  • Extremely fast deployment — claims to surpass the next-fastest solution by 173 days in time to value, with Five9 integration deployable in a single working session

  • Deep EHR integration with Epic including auto-syncing scheduling modifiers, appointment management, and prescription workflows

  • Proven ROI at scale with documented case studies showing $1M+ annual savings (Baptist Health), 8.8x ROI (Inova Health), and 56% reduction in call abandonment (Tampa General Hospital)

  • Comprehensive omnichannel coverage across voice, web chat, SMS, and mobile apps with unified Care Intelligence analytics and healthcare-specific benchmarking

Considerations

  • Exclusively focused on healthcare — not applicable for ecommerce, logistics, or other industries

  • English and Spanish language support only, which may limit adoption for health systems serving diverse multilingual populations

  • Some Proactive Px capabilities like billing support and care gap closure are listed as 'Coming Soon,' indicating the outbound platform is still maturing

  • Certain prescription management features require specific Epic modules (Willow Ambulatory), creating dependency on particular EHR configurations

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About Hyro

Hyro provides an agentic care communications platform purpose-built for healthcare organizations. The platform deploys AI-powered voice and chat agents across call centers, websites, mobile apps, and SMS to automate high-volume patient interactions such as appointment scheduling, FAQ resolution, prescription management, smart call routing, and MyChart password resets. Trusted by more than 50 leading health systems including Tampa General Hospital, Intermountain Health, Baptist Health, and Prisma Health, Hyro's AI agents engage over 30 million patients and span more than 2,500 hospitals, clinics, and healthcare facilities.

What sets Hyro apart is its responsible AI framework built on three pillars: explainability, control, and compliance. The platform provides full visibility into the logic behind AI outputs, contains hallucinations by limiting data sources to approved organizational content, and maintains strict adherence to HIPAA and patient data security regulations. Hyro's proprietary ACE (Agentic Conversational Engine) architecture maps conversations across more than 1,000 distinct patient intents, delivering granular visibility that pure large language model stacks cannot match. The platform also features Care Intelligence, an analytics layer that transforms AI agent interaction data into strategic access insights, complete with healthcare-specific benchmarks drawn from 100 million patient interactions.

Hyro is designed for rapid deployment, claiming to surpass the next-fastest solution by 173 days in time to value. The platform integrates directly with major EHR systems like Epic, contact center platforms including Five9, Cisco, Genesys, NICE, and Avaya, as well as CRM systems like Salesforce Health Cloud. Recent innovations include Proactive Px, an outbound patient engagement suite that powers AI-driven appointment reminders, referral management, prescription refills, and coverage disruption outreach. With approximately $95 million in total funding from investors including Healthier Capital, Norwest, ServiceNow Ventures, and Twilio, Hyro continues to expand its capabilities for health systems seeking to modernize patient access without adding operational complexity.

Integrations

  • Epic
  • Five9
  • Avaya
  • Genesys
  • NICE
  • Salesforce Health Cloud
  • Salesforce Service Cloud
  • Salesforce Service Cloud Voice
  • ServiceNow
  • Microsoft Azure
  • Twilio
  • Twilio Flex
  • RingCentral
  • Kyruus Health
  • Gozio Health
  • WebMD Ignite
  • Holon Solutions
  • Telesystem

Hyro

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